Ryze: Evidence-Enriched Data Synthesis from Biomedical Papers

Yeqi Huang, Yue Chen, Yanwei Ye, Guanhao Su, Luo Mai


Abstract
General-purpose VLMs remain unreliable for biomedical research because valid answers in scientific papers depend on evidence split across figures, tables, charts, captions, and referring text.Existing post-training pipelines are bottlenecked by costly expert annotation and by synthetic data that drops this evidence structure.We present Ryze, a fully automated system that converts raw biomedical papers into an evidence-enriched training set and a domain-specialized VLM.Ryze synthesizes QA pairs with complete supporting evidence (visual element, caption, extracted structure, and referring paragraphs), reduces layout and OCR errors via chart/table-aware extraction and LLM-based cleansing, and applies a two-stage post-training strategy combining supervised fine-tuning with reinforcement learning.Starting from Qwen3-VL-8B, Ryze produces BioVLM-8B at under $200, achieving 48.0% weighted accuracy on LAB-Bench—outperforming the base model by +12.6% and surpassing GPT-5.2 by +3.8%.We release Ryze as open source together with the trained BioVLM-8B model.
Anthology ID:
2026.acl-demo.73
Volume:
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 3: System Demonstrations)
Month:
July
Year:
2026
Address:
San Diego, California, United States
Editors:
Greg Durrett, Ping Jian
Venue:
ACL
SIG:
Publisher:
Association for Computational Linguistics
Note:
Pages:
743–749
Language:
URL:
https://preview.aclanthology.org/ingest-acl/2026.acl-demo.73/
DOI:
Bibkey:
Cite (ACL):
Yeqi Huang, Yue Chen, Yanwei Ye, Guanhao Su, and Luo Mai. 2026. Ryze: Evidence-Enriched Data Synthesis from Biomedical Papers. In Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 3: System Demonstrations), pages 743–749, San Diego, California, United States. Association for Computational Linguistics.
Cite (Informal):
Ryze: Evidence-Enriched Data Synthesis from Biomedical Papers (Huang et al., ACL 2026)
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PDF:
https://preview.aclanthology.org/ingest-acl/2026.acl-demo.73.pdf