Towards Effective and Efficient Multi-Agent Language Model Systems: Foundations, Prospects, and Applications

Xuan Wang, Shuxiang Cao, Yuchen Zhuang, Wenqi Shi


Abstract
Multi-agent systems powered by large language models (LLMs) offer a promising paradigm for tackling complex reasoning, decision-making, and problem-solving tasks. However, achieving both effectiveness and efficiency in such systems remains a critical challenge. This tutorial introduces recent advances in building effective and efficient multi-agent LLM systems, focusing on three core components. First, we discuss the design of individual LLM agents. We present state-of-the-art techniques for enabling capable agents using efficient and compact LLMs, including model distillation, dynamic routing, and memory- and compute efficient serving, providing a foundation for scalable and responsive agent design under resource constraints. Second, we cover coordination and communication among agents, crucial for collective performance, highlighting methods for improving multi-agent reasoning and decision-making through prompt and graph optimization, sycophancy mitigation, and structured LLM-based frameworks. Last, we explore real-world applications of LLM agents in areas such as industry, healthcare, quantum computing, and various scientific domains.
Anthology ID:
2026.acl-1.3
Volume:
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 5: Tutorial Abstracts)
Month:
July
Year:
2026
Address:
San Diego, California, USA
Editors:
Jacob Andreas, Kenton Murray
Venue:
ACL
SIG:
Publisher:
Association for Computational Linguistics
Note:
Pages:
5–6
Language:
URL:
https://preview.aclanthology.org/ingest-acl/2026.acl-1.3/
DOI:
Bibkey:
Cite (ACL):
Xuan Wang, Shuxiang Cao, Yuchen Zhuang, and Wenqi Shi. 2026. Towards Effective and Efficient Multi-Agent Language Model Systems: Foundations, Prospects, and Applications. In Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 5: Tutorial Abstracts), pages 5–6, San Diego, California, USA. Association for Computational Linguistics.
Cite (Informal):
Towards Effective and Efficient Multi-Agent Language Model Systems: Foundations, Prospects, and Applications (Wang et al., ACL 2026)
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PDF:
https://preview.aclanthology.org/ingest-acl/2026.acl-1.3.pdf