Subhas Roy


2026

Large language models achieve strong performance on biomedical question answering and summarization benchmarks, yet traditional evaluation metrics often fail to detect clinically significant factual errors. We introduce a unified evaluation framework that combines reference-based measures with evidence-grounded factuality verification to assess biomedical text generation. Evaluating four open-source models across three benchmarks (BioASQ, PubMedQA, MedLFQA), we find that 13.4?24.7% of generated claims are contradicted and 23?41% are unsupported, despite high lexical overlap scores. Our proposed Fact-Aligned Score (FAS) correlates strongly with claim-level verifiability (rho=0.68), substantially outperforming ROUGE-L (rho=0.41). We release an open-source toolkit with model outputs and analysis scripts to support reproducible factuality evaluation and safer deployment of biomedical LLMs.