Max Silverstein


2026

Most medical benchmarks for large language models test factual recall through multiple-choice questions, but on-the-ground physicians do not have the luxury of four options to choose from. NOHARM (Wu et al., 2025) demonstrated this limitation using 100 real eConsult cases annotated by 29 board-certified physicians, showing that action-level evaluation reveals omission and commission failure modes invisible to multiple-choice tests. However, NOHARM’s cases are closed and their creation required substantial expert physician time, creating a human bottleneck that limits the scalability and openness of this evaluation approach. We present MedAct, an open replication of NOHARM’s evaluation methodology using synthetically generated cases. Our contribution is a multi-stage generation pipeline that uses language models grounded in clinical practice guidelines to produce 100 cases across ten specialties, each containing roughly 50 plausible next-step actions labeled as Appropriate or Inappropriate using NOHARM’sscoring framework. The pipeline includes structural quality controls: 83 of 100 cases pass all five automated checks, and answer-leaking language appears in only 0.06% of actions. In a pilot evaluation of nine contemporary LLMs using this synthetic benchmark, we observe patterns consistent with NOHARM’s findings on human-curated cases, including that omissions dominate error volume while commissions dominate severe errors. We release all cases, rubrics, generation tooling, and scoring code openly, removing the human-bottleneck barrier to action-level clinical LLM evaluation.