Overview of #SMM4H-HeaRD 2026 – Task 6: Predicting TNM staging from pathology reports

Jose Miguel Acitores Cortina, Jacob S. Berkowitz, Nadine A. Friedrich, Nicholas P Tatonetti


Abstract
This paper provides an overview of Task 6 from the Social Media Mining for Health/Health Real-World Data shared task (#SMM4H-HeaRD 2026), which focused on predicting TNM staging from pathology reports from TCGA. Seven teams submitted systems spanning fine-tuned clinical encoders, open-source generative LLMs, and closed-source API models. On a straightforward test set, most teams achieved near-perfect F1 scores (average 0.993, 0.972, and 0.957 for T, N, and M). However, on a harder tiebreak set where explicit TNM notation was removed and staging had to be inferred from clinical descriptions, performance dropped substantially (average 0.725, 0.783, and 0.846). Notably, the two teams using large closed-source API models generalized best to the harder set, achieving the highest T and N scores despite not leading on the easy set. These results suggest that while fine-tuned domain-specific encoders excel at surface-level extraction, larger general-purpose LLMs may be more robust when staging must be inferred from contextual clinical findings. All teams surpassed baseline overall performance on both test sets.
Anthology ID:
2026.smm4h-1.50
Volume:
Proceedings of the 11th Social Media Mining for Health Research and Applications (SMM4H-HeaRD 2026) Workshop and Shared Tasks
Month:
July
Year:
2026
Address:
San Diego, United States
Editors:
Guillermo Lopez-Garcia, Graciela Gonzalez-Hernandez
Venues:
SMM4H | WS
SIG:
Publisher:
Association for Computational Linguistics
Note:
Pages:
332–337
Language:
URL:
https://preview.aclanthology.org/ingest-acl-workshops/2026.smm4h-1.50/
DOI:
Bibkey:
Cite (ACL):
Jose Miguel Acitores Cortina, Jacob S. Berkowitz, Nadine A. Friedrich, and Nicholas P Tatonetti. 2026. Overview of #SMM4H-HeaRD 2026 – Task 6: Predicting TNM staging from pathology reports. In Proceedings of the 11th Social Media Mining for Health Research and Applications (SMM4H-HeaRD 2026) Workshop and Shared Tasks, pages 332–337, San Diego, United States. Association for Computational Linguistics.
Cite (Informal):
Overview of #SMM4H-HeaRD 2026 – Task 6: Predicting TNM staging from pathology reports (Acitores Cortina et al., SMM4H 2026)
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PDF:
https://preview.aclanthology.org/ingest-acl-workshops/2026.smm4h-1.50.pdf