Do Syntactic Features Help Biomedical Relation Extraction? An Empirical Study of Verb Token and Dependency Graph Augmentation

Mustafa Sikder, Ernest Kwegyir-Afful


Abstract
We investigate whether explicit syntactic features improve transformer-based biomedical relation extraction when added to typed entity marker pooling. We evaluate two augmentation strategies on top of BiomedBERT: (1) verb token augmentation, which concatenates the hidden state of the dependency root verb to the entity representations, and (2) a two-layer graph convolutional network (GCN) that refines encoder hidden states over the dependency parse before entity pooling. We experimented on three biomedical datasets: ChemProt, DDI, and AIMed with three random seeds. We found neither strategy consistently outperformed the entity-only baseline. The GCN yielded modest gains on AIMed (+0.007 F1) and ChemProt (+0.003 F1) but decreased performance on DDI (-0.013 F1). Verb token augmentation helps only on AIMed (+0.004 F1) and underperforms on the other two datasets. A syntactic characterization of the datasets reveals that DDI has substantially higher passive voice usage (50.7\% of relation-bearing sentences) than AIMed (27.0\%) or ChemProt (30.9\%), suggesting that syntactic augmentation is more effective when sentences exhibit active verbal structure with semantically informative predicates. These results suggest that corpus-level syntactic characteristics, particularly passive voice usage, may moderate the utility of explicit syntactic augmentation, though the small magnitude of observed differences warrants caution in interpretation.
Anthology ID:
2026.bionlp-1.12
Volume:
BioNLP 2026
Month:
July
Year:
2026
Address:
San Diego, California
Editors:
Dina Demner-Fushman, Sophia Ananiadou, Kirk Roberts, Junichi Tsujii
Venues:
BioNLP | WS
SIG:
Publisher:
Association for Computational Linguistics
Note:
Pages:
128–134
Language:
URL:
https://preview.aclanthology.org/ingest-acl-workshops/2026.bionlp-1.12/
DOI:
Bibkey:
Cite (ACL):
Mustafa Sikder and Ernest Kwegyir-Afful. 2026. Do Syntactic Features Help Biomedical Relation Extraction? An Empirical Study of Verb Token and Dependency Graph Augmentation. In BioNLP 2026, pages 128–134, San Diego, California. Association for Computational Linguistics.
Cite (Informal):
Do Syntactic Features Help Biomedical Relation Extraction? An Empirical Study of Verb Token and Dependency Graph Augmentation (Sikder & Kwegyir-Afful, BioNLP 2026)
Copy Citation:
PDF:
https://preview.aclanthology.org/ingest-acl-workshops/2026.bionlp-1.12.pdf