Eligibility criteria (EC) refer to a set of conditions an individual must meet to participate in a clinical trial, defining the study population and minimizing potential risks to patients. Previous research in clinical trial design has been primarily focused on searching for similar trials and generating EC within manual instructions, employing similarity-based performance metrics, which may not fully reflect human judgment. In this study, we propose a novel task of recommending EC based on clinical trial information, including trial titles, and introduce an automatic evaluation framework to assess the clinical validity of the EC recommendation model. Our new approach, known as CReSE (Contrastive learning and Rephrasing-based and Clinical Relevance-preserving Sentence Embedding), represents EC through contrastive learning and rephrasing via large language models (LLMs). The CReSE model outperforms existing language models pre-trained on the biomedical domain in EC clustering. Additionally, we have curated a benchmark dataset comprising 3.2M high-quality EC-title pairs extracted from 270K clinical trials available on ClinicalTrials.gov. The EC recommendation models achieve commendable performance metrics, with 49.0% precision@1 and 44.2% MAP@5 on our evaluation framework. We expect that our evaluation framework built on the CReSE model will contribute significantly to the development and assessment of the EC recommendation models in terms of clinical validity.

The UNESCO World Heritage List (WHL) includes the exceptionally valuable cultural and natural heritage to be preserved for mankind. Evaluating and justifying the Outstanding Universal Value (OUV) is essential for each site inscribed in the WHL, and yet a complex task, even for experts, since the selection criteria of OUV are not mutually exclusive. Furthermore, manual annotation of heritage values and attributes from multi-source textual data, which is currently dominant in heritage studies, is knowledge-demanding and time-consuming, impeding systematic analysis of such authoritative documents in terms of their implications on heritage management. This study applies state-of-the-art NLP models to build a classifier on a new dataset containing Statements of OUV, seeking an explainable and scalable automation tool to facilitate the nomination, evaluation, research, and monitoring processes of World Heritage sites. Label smoothing is innovatively adapted to improve the model performance by adding prior inter-class relationship knowledge to generate soft labels. The study shows that the best models fine-tuned from BERT and ULMFiT can reach 94.3% top-3 accuracy. A human study with expert evaluation on the model prediction shows that the models are sufficiently generalizable. The study is promising to be further developed and applied in heritage research and practice.

We Microsoft Research Asia made submissions to 11 language directions in the WMT19 news translation tasks. We won the first place for 8 of the 11 directions and the second place for the other three. Our basic systems are built on Transformer, back translation and knowledge distillation. We integrate several of our rececent techniques to enhance the baseline systems: multi-agent dual learning (MADL), masked sequence-to-sequence pre-training (MASS), neural architecture optimization (NAO), and soft contextual data augmentation (SCA).