In knowledge-intensive domains like scientific research, effective decisions rely on organizing and retrieving intricate data. Knowledge graphs (KGs) help by structuring entities, relations, and contextual dependencies, but building KGs in such domains is challenging due to inherent complexity, manual effort, and rapid evolution. Inspired by how humans organize knowledge hierarchically, we propose Tree-KG, an expandable framework that combines structured domain texts with advanced semantic techniques. First, Tree-KG builds a tree-like graph from textbook structures using large language models (LLMs) and domain-specific entities, creating an explicit KG. Then, through iterative expansion with flexible, predefined operators, it uncovers hidden KG while preserving semantic coherence. Experiments demonstrate that Tree-KG consistently surpasses competing methods, achieving the highest F1 scores (12–16% above the second-best), with notable performance (F1 0.81) on the Text-Annotated dataset, highlighting its effectiveness in extracting high-quality information from source texts. Additionally, Tree-KG provides superior structural alignment, domain-specific extraction, and cost-efficiency, delivering robust results with reduced token usage and adaptable, resource-conscious deployment.

Given the input radiology images, the objective of radiology report generation is to produce accurate and comprehensive medical reports, which typically include multiple descriptive clinical sentences associated with different phenotypes. Most existing works have relied on a pre-trained vision encoder to extract the visual representations of the images. In this study, we propose a phenotype-driven medical vision-language representation learning framework to efficiently bridge the gap between visual and textual modalities for improved text-oriented generation. In contrast to conventional methods which learn medical vision-language representations by contrasting images with entire reports, our approach learns more fine-grained representations by contrasting images with each sentence within the reports. The learned fine-grained representations can be used to improve radiology report generation. The experiments on two widely-used datasets MIMIC-CXR and IU X-ray demonstrate that our method can achieve promising performances and substantially outperform the conventional vision-language representation learning methods.