Drug-drug interactions (DDIs) arise when multiple drugs are administered concurrently. Accurately predicting the specific mechanisms underlying DDIs (named DDI events or DDIEs) is critical for the safe clinical use of drugs. DDIEs are typically represented as textual descriptions. However, most computational methods focus more on predicting the DDIE class label over generating human-readable natural language increasing clinicians’ interpretation costs. Furthermore, current methods overlook the fact that each drug assumes distinct biological functions in a DDI, which, when used as input context, can enhance the understanding of the DDIE process and benefit DDIE generation by the language model (LM). In this work, we propose a novel pairwise knowledge-augmented generative method (termed PKAG-DDI) for DDIE text generation. It consists of a pairwise knowledge selector efficiently injecting structural information between drugs bidirectionally and simultaneously to select pairwise biological functions from the knowledge set, and a pairwise knowledge integration strategy that matches and integrates the selected biological functions into the LM. Experiments on two professional datasets show that PKAG-DDI outperforms existing methods in DDIE text generation, especially in challenging inductive scenarios, indicating its practicality and generalization.

Spelling errors in Chinese idioms frequently occur due to various types of misspellings and optical character recognition (OCR) errors in daily learning and usage. Achieving automatic error correction for Chinese idioms is one of the important natural language processing tasks, as it helps improve the quality of Chinese texts as well as language learning. Existing methods, such as edit distance and custom dictionary approaches, suffer from limited error correction capability, low computational efficiency, and weak flexibility. To address these limitations, this paper proposes a novel automatic error correction method for Chinese idioms based on the hidden Markov model (HMM). Specifically, the generation process of idiom spelling errors is modeled using an HMM, transforming the idiom correction problem into a matching task between erroneous idioms and legitimate idioms. By constructing a legitimate idiom table and a Chinese character confusion set, a prototype system for idiom correction was developed, and performance testing was completed. Experiment results demonstrate that the proposed model is simpler with fewer parameters and has lower computational complexity while exhibiting stronger error correction capability and parameter robustness as compared to existing methods. It can more flexibly correct diverse types of idiom errors, showing high potential application value.