Prader-Willi syndrome
Other namesLabhart-Willi syndrome, Prader's syndrome, Prader-Labhart-Willi-Fanconi syndrome
Pronunciation
  • /ˈprɑːdər ˈvɪli/, /ˈprdər wɪli/, /ˈprɑːdər ˈwɪli/
SpecialtyMedical genetics, psychiatry, pediatrics
SymptomsBabies: weak muscles, poor feeding, slow development
Children: constantly hungry, intellectual impairment, behavioural problems
ComplicationsObesity, type 2 diabetes
DurationLifelong
CausesGenetic disorder (typically new mutation)
Differential diagnosisSpinal muscular atrophy, congenital myotonic dystrophy, familial obesity
TreatmentFeeding tubes, strict food supervision, exercise program, counseling
MedicationGrowth hormone therapy
Frequency1 in 10,000–30,000 people