Large Language Model (LLM)-based Multi-agent Systems (MAS) have demonstrated remarkable capabilities in various complex tasks, ranging from collaborative problem-solving to autonomous decision-making. However, as these systems become increasingly integrated into critical applications, their vulnerability to adversarial attacks, misinformation propagation, and unintended behaviors have raised significant concerns. To address this challenge, we introduce G-Safeguard, a topology-guided security lens and treatment for robust LLM-MAS, which leverages graph neural networks to detect anomalies on the multi-agent utterance graph and employ topological intervention for attack remediation. Extensive experiments demonstrate that G-Safeguard: (I) exhibits significant effectiveness under various attack strategies, recovering over 40% of the performance for prompt injection; (II) is highly adaptable to diverse LLM backbones and large-scale MAS; (III) can seamlessly combine with mainstream MAS with security guarantees.

Large language models (LLMs) have fueled significant progress in intelligent Multi-agent Systems (MAS), with expanding academic and industrial applications. However, safeguarding these systems from malicious queries receives relatively little attention, while methods for single-agent safety are challenging to transfer. In this paper, we explore MAS safety from a topological perspective, aiming at identifying structural properties that enhance security. To this end, we propose NetSafe framework, unifying diverse MAS workflows via iterative RelCom interactions to enable generalized analysis. We identify several critical phenomena for MAS under attacks (misinformation, bias, and harmful content), termed as Agent Hallucination, Aggregation Safety and Security Bottleneck. Furthermore, we verify that highly connected and larger systems are more vulnerable to adversarial spread, with task performance in a Star Graph Topology decreasing by 29.7%. In conclusion, our work introduces a new perspective on MAS safety and discovers unreported phenomena, offering insights and posing challenges to the community.