Training classification models on clinical speech is a time-saving and effective solution for many healthcare challenges, such as screening for Alzheimer’s Disease over the phone. One of the primary limiting factors of the success of artificial intelligence (AI) solutions is the amount of relevant data available. Clinical data is expensive to collect, not sufficient for large-scale machine learning or neural methods, and often not shareable between institutions due to data protection laws. With the increasing demand for AI in health systems, generating synthetic clinical data that maintains the nuance of underlying patient pathology is the next pressing task. Previous work has shown that automated evaluation of clinical speech tasks via automatic speech recognition (ASR) is comparable to manually annotated results in diagnostic scenarios even though ASR systems produce errors during the transcription process. In this work, we propose to generate synthetic clinical data by simulating ASR deletion errors on the transcript to produce additional data. We compare the synthetic data to the real data with traditional machine learning methods to test the feasibility of the proposed method. Using a dataset of 50 cognitively impaired and 50 control Dutch speakers, ten additional data points are synthetically generated for each subject, increasing the training size for 100 to 1000 training points. We find consistent and comparable performance of models trained on only synthetic data (AUC=0.77) to real data (AUC=0.77) in a variety of traditional machine learning scenarios. Additionally, linear models are not able to distinguish between real and synthetic data.

A lot of real-world phenomena are complex and cannot be captured by single task annotations. This causes a need for subsequent annotations, with interdependent questions and answers describing the nature of the subject at hand. Even in the case a phenomenon is easily captured by a single task, the high specialisation of most annotation tools can result in having to switch to another tool if the task only slightly changes. We introduce HUMAN, a novel web-based annotation tool that addresses the above problems by a) covering a variety of annotation tasks on both textual and image data, and b) the usage of an internal deterministic state machine, allowing the researcher to chain different annotation tasks in an interdependent manner. Further, the modular nature of the tool makes it easy to define new annotation tasks and integrate machine learning algorithms e.g., for active learning. HUMAN comes with an easy-to-use graphical user interface that simplifies the annotation task and management.

There is growing evidence that changes in speech and language may be early markers of dementia, but much of the previous NLP work in this area has been limited by the size of the available datasets. Here, we compare several methods of domain adaptation to augment a small French dataset of picture descriptions (n = 57) with a much larger English dataset (n = 550), for the task of automatically distinguishing participants with dementia from controls. The first challenge is to identify a set of features that transfer across languages; in addition to previously used features based on information units, we introduce a new set of features to model the order in which information units are produced by dementia patients and controls. These concept-based language model features improve classification performance in both English and French separately, and the best result (AUC = 0.89) is achieved using the multilingual training set with a combination of information and language model features.

The Semantic Verbal Fluency (SVF) task is a classical neuropsychological assessment where persons are asked to produce words belonging to a semantic category (e.g., animals) in a given time. This paper introduces a novel method of temporal analysis for SVF tasks utilizing time intervals and applies it to a corpus of elderly Swedish subjects (mild cognitive impairment, subjective cognitive impairment and healthy controls). A general decline in word count and lexical frequency over the course of the task is revealed, as well as an increase in word transition times. Persons with subjective cognitive impairment had a higher word count during the last intervals, but produced words of the same lexical frequencies. Persons with MCI had a steeper decline in both word count and lexical frequencies during the third interval. Additional correlations with neuropsychological scores suggest these findings are linked to a person’s overall vocabulary size and processing speed, respectively. Classification results improved when adding the novel features (AUC=0.72), supporting their diagnostic value.

This paper summarizes the latest, final version of ISO standard 24617-2 ``Semantic annotation framework, Part 2: Dialogue acts"""". Compared to the preliminary version ISO DIS 24617-2:2010, described in Bunt et al. (2010), the final version additionally includes concepts for annotating rhetorical relations between dialogue units, defines a full-blown compositional semantics for the Dialogue Act Markup Language DiAML (resulting, as a side-effect, in a different treatment of functional dependence relations among dialogue acts and feedback dependence relations); and specifies an optimally transparent XML-based reference format for the representation of DiAML annotations, based on the systematic application of the notion of `ideal concrete syntax'. We describe these differences and briefly discuss the design and implementation of an incremental method for dialogue act recognition, which proves the usability of the ISO standard for automatic dialogue annotation.

This paper describes an ISO project which aims at developing a standard for annotating spoken and multimodal dialogue with semantic information concerning the communicative functions of utterances, the kind of semantic content they address, and their relations with what was said and done earlier in the dialogue. The project, ISO 24617-2 ""Semantic annotation framework, Part 2: Dialogue acts"", is currently at DIS stage. The proposed annotation schema distinguishes 9 orthogonal dimensions, allowing each functional segment in dialogue to have a function in each of these dimensions, thus accounting for the multifunctionality that utterances in dialogue often have. A number of core communicative functions is defined in the form of ISO data categories, available at http://semantic-annotation.uvt.nl/dialogue-acts/iso-datcats.pdf; they are divided into ""dimension-specific"" functions, which can be used only in a particular dimension, such as Turn Accept in the Turn Management dimension, and ""general-purpose"" functions, which can be used in any dimension, such as Inform and Request. An XML-based annotation language, ""DiAML"" is defined, with an abstract syntax, a semantics, and a concrete syntax.