Recent work uses a Siamese Network, initialized with BioWordVec embeddings (distributed word embeddings), for predicting synonymy among biomedical terms to automate a part of the UMLS (Unified Medical Language System) Metathesaurus construction process. We evaluate the use of contextualized word embeddings extracted from nine different biomedical BERT-based models for synonym prediction in the UMLS by replacing BioWordVec embeddings with embeddings extracted from each biomedical BERT model using different feature extraction methods. Finally, we conduct a thorough grid search, which prior work lacks, to find the best set of hyperparameters. Surprisingly, we find that Siamese Networks initialized with BioWordVec embeddings still out perform the Siamese Networks initialized with embedding extracted from biomedical BERT model.

Conversational Agents (CAs) powered with deep language models (DLMs) have shown tremendous promise in the domain of mental health. Prominently, the CAs have been used to provide informational or therapeutic services (e.g., cognitive behavioral therapy) to patients. However, the utility of CAs to assist in mental health triaging has not been explored in the existing work as it requires a controlled generation of follow-up questions (FQs), which are often initiated and guided by the mental health professionals (MHPs) in clinical settings. In the context of ‘depression’, our experiments show that DLMs coupled with process knowledge in a mental health questionnaire generate 12.54% and 9.37% better FQs based on similarity and longest common subsequence matches to questions in the PHQ-9 dataset respectively, when compared with DLMs without process knowledge support.Despite coupling with process knowledge, we find that DLMs are still prone to hallucination, i.e., generating redundant, irrelevant, and unsafe FQs. We demonstrate the challenge of using existing datasets to train a DLM for generating FQs that adhere to clinical process knowledge. To address this limitation, we prepared an extended PHQ-9 based dataset, PRIMATE, in collaboration with MHPs. PRIMATE contains annotations regarding whether a particular question in the PHQ-9 dataset has already been answered in the user’s initial description of the mental health condition. We used PRIMATE to train a DLM in a supervised setting to identify which of the PHQ-9 questions can be answered directly from the user’s post and which ones would require more information from the user. Using performance analysis based on MCC scores, we show that PRIMATE is appropriate for identifying questions in PHQ-9 that could guide generative DLMs towards controlled FQ generation (with minimal hallucination) suitable for aiding triaging. The dataset created as a part of this research can be obtained from https://github.com/primate-mh/Primate2022

Existing studies on using social media for deriving mental health status of users focus on the depression detection task. However, for case management and referral to psychiatrists, health-care workers require practical and scalable depressive disorder screening and triage system. This study aims to design and evaluate a decision support system (DSS) to reliably determine the depressive triage level by capturing fine-grained depressive symptoms expressed in user tweets through the emulation of the Patient Health Questionnaire-9 (PHQ-9) that is routinely used in clinical practice. The reliable detection of depressive symptoms from tweets is challenging because the 280-character limit on tweets incentivizes the use of creative artifacts in the utterances and figurative usage contributes to effective expression. We propose a novel BERT based robust multi-task learning framework to accurately identify the depressive symptoms using the auxiliary task of figurative usage detection. Specifically, our proposed novel task sharing mechanism,co-task aware attention, enables automatic selection of optimal information across the BERT lay-ers and tasks by soft-sharing of parameters. Our results show that modeling figurative usage can demonstrably improve the model’s robustness and reliability for distinguishing the depression symptoms.

One of the cardinal tasks in achieving robust medical question answering systems is textual entailment. The existing approaches make use of an ensemble of pre-trained language models or data augmentation, often to clock higher numbers on the validation metrics. However, two major shortcomings impede higher success in identifying entailment: (1) understanding the focus/intent of the question and (2) ability to utilize the real-world background knowledge to capture the con-text beyond the sentence. In this paper, we present a novel Medical Knowledge-Enriched Textual Entailment framework that allows the model to acquire a semantic and global representation of the input medical text with the help of a relevant domain-specific knowledge graph. We evaluate our framework on the benchmark MEDIQA-RQE dataset and manifest that the use of knowledge-enriched dual-encoding mechanism help in achieving an absolute improvement of 8.27% over SOTA language models.

In recent past, social media has emerged as an active platform in the context of healthcare and medicine. In this paper, we present a study where medical user’s opinions on health-related issues are analyzed to capture the medical sentiment at a blog level. The medical sentiments can be studied in various facets such as medical condition, treatment, and medication that characterize the overall health status of the user. Considering these facets, we treat analysis of this information as a multi-task classification problem. In this paper, we adopt a novel adversarial learning approach for our multi-task learning framework to learn the sentiment’s strengths expressed in a medical blog. Our evaluation shows promising results for our target tasks.

This work addresses challenges arising from extracting entities from textual data, including the high cost of data annotation, model accuracy, selecting appropriate evaluation criteria, and the overall quality of annotation. We present a framework that integrates Entity Set Expansion (ESE) and Active Learning (AL) to reduce the annotation cost of sparse data and provide an online evaluation method as feedback. This incremental and interactive learning framework allows for rapid annotation and subsequent extraction of sparse data while maintaining high accuracy. We evaluate our framework on three publicly available datasets and show that it drastically reduces the cost of sparse entity annotation by an average of 85% and 45% to reach 0.9 and 1.0 F-Scores respectively. Moreover, the method exhibited robust performance across all datasets.

Extracting location names from informal and unstructured social media data requires the identification of referent boundaries and partitioning compound names. Variability, particularly systematic variability in location names (Carroll, 1983), challenges the identification task. Some of this variability can be anticipated as operations within a statistical language model, in this case drawn from gazetteers such as OpenStreetMap (OSM), Geonames, and DBpedia. This permits evaluation of an observed n-gram in Twitter targeted text as a legitimate location name variant from the same location-context. Using n-gram statistics and location-related dictionaries, our Location Name Extraction tool (LNEx) handles abbreviations and automatically filters and augments the location names in gazetteers (handling name contractions and auxiliary contents) to help detect the boundaries of multi-word location names and thereby delimit them in texts. We evaluated our approach on 4,500 event-specific tweets from three targeted streams to compare the performance of LNEx against that of ten state-of-the-art taggers that rely on standard semantic, syntactic and/or orthographic features. LNEx improved the average F-Score by 33-179%, outperforming all taggers. Further, LNEx is capable of stream processing.