InfAL: Inference Time Adversarial Learning for Improving Research Ideation

Sikun Guo, Amir Hassan Shariatmadari, Peng Wang, Albert Huang, Aidong Zhang


Abstract
Advancements in Large Language Models (LLMs) have opened new opportunities for scientific discovery by assisting researchers in generating novel hypotheses and ideas. In this process, a major challenge is how to optimally and efficiently utilize LLMs’ parametric knowledge obtained from their pretraining process. Inspired by Generative Adversarial Networks (GANs), we propose inference time adversarial learning (termed InfAL), implemented through multi-LLM-agent interactions, to enhance research ideation. This approach optimizes the utilization of LLMs’ parametric knowledge without requiring additional model training, making adversarial learning efficient and context-driven. To evaluate the quality of generated ideas, we propose a relative quality ranking metric as a scalable alternative to human evaluation. Our results show that InfAL significantly improves idea generation, with GPT-4o achieving a 21% increase in novelty and a 322% increase in feasibility, demonstrating its transformative potential for driving innovation in scientific research.
Anthology ID:
2025.findings-emnlp.667
Volume:
Findings of the Association for Computational Linguistics: EMNLP 2025
Month:
November
Year:
2025
Address:
Suzhou, China
Editors:
Christos Christodoulopoulos, Tanmoy Chakraborty, Carolyn Rose, Violet Peng
Venue:
Findings
SIG:
Publisher:
Association for Computational Linguistics
Note:
Pages:
12501–12522
Language:
URL:
https://preview.aclanthology.org/author-page-yu-wang-polytechnic/2025.findings-emnlp.667/
DOI:
10.18653/v1/2025.findings-emnlp.667
Bibkey:
Cite (ACL):
Sikun Guo, Amir Hassan Shariatmadari, Peng Wang, Albert Huang, and Aidong Zhang. 2025. InfAL: Inference Time Adversarial Learning for Improving Research Ideation. In Findings of the Association for Computational Linguistics: EMNLP 2025, pages 12501–12522, Suzhou, China. Association for Computational Linguistics.
Cite (Informal):
InfAL: Inference Time Adversarial Learning for Improving Research Ideation (Guo et al., Findings 2025)
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https://preview.aclanthology.org/author-page-yu-wang-polytechnic/2025.findings-emnlp.667.pdf
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