RGAR: Recurrence Generation-augmented Retrieval for Factual-aware Medical Question Answering

Sichu Liang, Linhai Zhang, Hongyu Zhu, Wenwen Wang, Yulan He, Deyu Zhou


Abstract
Medical question answering fundamentally relies on accurate clinical knowledge. The dominant paradigm, Retrieval-Augmented Generation (RAG), acquires expertise conceptual knowledge from large-scale medical corpus to guide general-purpose large language models (LLMs) in generating trustworthy answers. However, existing retrieval approaches often overlook the patient-specific factual knowledge embedded in Electronic Health Records (EHRs), which limits the contextual relevance of retrieved conceptual knowledge and hinders its effectiveness in vital clinical decision-making. This paper introduces RGAR, a recurrence generation-augmented retrieval framework that synergistically retrieves both factual and conceptual knowledge from dual sources (i.e., EHRs and the corpus), allowing mutual refinement through iterative interaction. Across three factual-aware medical QA benchmarks, RGAR establishes new state-of-the-art performance among medical RAG systems. Notably, RGAR enables the Llama-3.1-8B-Instruct model to surpass the considerably larger GPT-3.5 augmented with traditional RAG. Our findings demonstrate the benefit of explicitly mining patient-specific factual knowledge during retrieval, consistently improving generation quality and clinical relevance.
Anthology ID:
2025.findings-emnlp.214
Volume:
Findings of the Association for Computational Linguistics: EMNLP 2025
Month:
November
Year:
2025
Address:
Suzhou, China
Editors:
Christos Christodoulopoulos, Tanmoy Chakraborty, Carolyn Rose, Violet Peng
Venue:
Findings
SIG:
Publisher:
Association for Computational Linguistics
Note:
Pages:
4006–4033
Language:
URL:
https://preview.aclanthology.org/author-page-yu-wang-polytechnic/2025.findings-emnlp.214/
DOI:
10.18653/v1/2025.findings-emnlp.214
Bibkey:
Cite (ACL):
Sichu Liang, Linhai Zhang, Hongyu Zhu, Wenwen Wang, Yulan He, and Deyu Zhou. 2025. RGAR: Recurrence Generation-augmented Retrieval for Factual-aware Medical Question Answering. In Findings of the Association for Computational Linguistics: EMNLP 2025, pages 4006–4033, Suzhou, China. Association for Computational Linguistics.
Cite (Informal):
RGAR: Recurrence Generation-augmented Retrieval for Factual-aware Medical Question Answering (Liang et al., Findings 2025)
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https://preview.aclanthology.org/author-page-yu-wang-polytechnic/2025.findings-emnlp.214.pdf
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