Transformer-based Large Language Models (LLMs) have achieved remarkable success across various domains, including clinical language processing, where they enable state-of-the-art performance in numerous tasks. Like all deep learning models, LLMs are susceptible to inference attacks that exploit sensitive attributes seen during training. AnonCAT, a RoBERTa-based masked language model, has been fine-tuned to de-identify sensitive clinical textual data. The community has a responsibility to explore the privacy risks of these models. This work proposes an attack method to infer sensitive named entities used in the training of AnonCAT models. We perform three experiments; the privacy implications of generating multiple names, the impact of white-box and black-box on attack inference performance, and the privacy-enhancing effects of Differential Privacy (DP) when applied to AnonCAT. By providing real textual predictions and privacy leakage metrics, this research contributes to understanding and mitigating the potential risks associated with exposing LLMs in sensitive domains like healthcare.

Clinical coding is currently a labour-intensive, error-prone, but a critical administrative process whereby hospital patient episodes are manually assigned codes by qualified staff from large, standardised taxonomic hierarchies of codes. Automating clinical coding has a long history in NLP research and has recently seen novel developments setting new benchmark results. A popular dataset used in this task is MIMIC-III, a large database of clinical free text notes and their associated codes amongst other data. We argue for the reconsideration of the validity MIMIC-III’s assigned codes, as MIMIC-III has not undergone secondary validation. This work presents an open-source, reproducible experimental methodology for assessing the validity of EHR discharge summaries. We exemplify the methodology with MIMIC-III discharge summaries and show the most frequently assigned codes in MIMIC-III are undercoded up to 35%.

An interface for building, improving and customising a given Named Entity Recognition and Linking (NER+L) model for biomedical domain text, and the efficient collation of accurate research use case specific training data and subsequent model training. Screencast demo available here: https://www.youtube.com/watch?v=lM914DQjvSo